Analyses were also positive for other opioids and metabolites in 6 clients, predominantly codeine and oxycodone. One client was positive for both fentanyl and heroin. Seven clients tested positive for fentanyl. Clients' urine samples were subsequently analysed in a collaborating laboratory. In some cases, false negative results occurred. Immunoassays for fentanyl were used in the service. Relapses resulted in treatment disengagement. The clients had a history of past opioid use, including heroin. Clients presented with difficulties breathing and pains in the lungs. We report a case series of 14 drug addiction treatment entrants, who entered treatment in a service located in the region of Southern Denmark from August 2015 to December 2015 for smoking fentanyl patches. Fentanyl is one of these synthetic opioids that is typically prescribed as a transdermal patch for pain that requires continuous pain relief and has been the focus of investigation due to reports of overdose and death. The increase in opioid prescribing in many European countries over the last decade has raised concerns about associated diversion, overdose, and mortality.
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